Ergosterol Attenuates Isoproterenol-Induced Myocardial Cardiotoxicity.

In conclusion, we provide both in vitro and in vivo evidence that ER significantly enhances Nrf2-mediated anti-oxidative activities, and exerts a protective effect on cardiomyocyte apoptosis. ER could be considered as a potential therapeutic agent to prevent myocardial injury.
PMID: 32361914 [PubMed - as supplied by publisher]

Source: Cardiovascular Toxicology - May 1, 2020 Category: Cardiology Authors: Xie Q, Li S, Gao Y, Jin L, Dai C, Song J Tags: Cardiovasc Toxicol Source Type: research