Common disorders: It's not the genes themselves, but how they are controlled

(Case Western Reserve University) Many rare disorders are caused by gene mutation. Yet until now the underlying genetic cause of more common conditions has evaded scientists for years. New research from Case Western Reserve University to appear in Genome Research finds that six common diseases arise from DNA changes located outside genes. The study from the laboratory of Peter Scacheri, PhD, shows that multiple DNA changes, or variants, work in concert to affect genes, leading to autoimmune diseases.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news