Neurofilament light chain and MRI volume parameters as markers of neurodegeneration in multiple sclerosis.

CONCLUSION: Study shows association of pNfL with Wbv, presence of brain atrophy and EDSS, and strong correlation of EDSS with multiple MRI volume parameters. We did not confirm association pNfL with disease activity. Our data suggest that pNfL and MRI volume parameters could be considered as biomarkers of neurodegeneration in MS. PMID: 32338853 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32338853?dopt=Abstract

Source: Neuroendocrinology Letters - April 29, 2020 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research