Chronic Binge Alcohol Exposure During Pregnancy Alters mTOR System in Rat Fetal Hippocampus.

CONCLUSION: We conclude that chronic binge alcohol exposure during pregnancy alters mTORC1 signaling pathway in the fetal hippocampus. We conjecture that this dysregulation of mTOR protein expression, its activity, and downstream proteins may play a critical role in FASD neurobiological phenotypes. PMID: 32333810 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32333810?dopt=Abstract

Source: Alcoholism, Clinical and Experimental Research - April 24, 2020 Category: Addiction Authors: Lee J, Lunde-Young R, Naik V, Ramirez J, Orzabal M, Ramadoss J Tags: Alcohol Clin Exp Res Source Type: research