Hypolipidemic effect of the polysaccharides extracted from pumpkin by celluase-assisted method on mice.

This study was conducted to investigate the hypolipidemic effect of the polysaccharide isolated from pumpkin (PP). Male Sprague-Dawley rats were divided into three groups and treated with diets containing either high fat, PP, or normal fat. Oral administration of PP could significantly decrease the levels of plasma triacylglycerol (TG), total cholesterol (TC), and plasma low-density lipoprotein cholesterol and increase the levels of faecal fat, cholesterol, and plasma high-density lipoprotein cholesterol. Therefore, results suggest that PP had a high hypolipidaemic activity and could be explored as a possible agent for hyperlipidemia. PMID: 24325857 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24325857?dopt=Abstract

Source: International Journal of Biological Macromolecules - December 7, 2013 Category: Biochemistry Authors: Zhao XH, Qian L, Yin DL, Zhou Y Tags: Int J Biol Macromol Source Type: research