Matrix-assisted laser desorption/ionization in-source decay mass spectrometry analysis of human insulin and insulin analogues for the identification of insulin from insulin preparations

ConclusionsThe MALDI-ISD method is a rapid and convenient approach to identify human insulin and six insulin analogues that are components of all insulin preparations sold in Japan. In particular, this method can discriminate human insulin from insulin lispro, both of which have identical molecular weights, and therefore identifying them is difficult using conventional methods.

http://link.springer.com/10.1007/s11419-020-00532-z

Source: Forensic Toxicology - April 23, 2020 Category: Forensic Medicine Source Type: research