Pseudomonas Aeruginosa as the Main Causative Agent of Osteomyelitis and its Susceptibility to Antibiotics
Drug Res (Stuttg) DOI: 10.1055/a-1150-2372Surgical activity is increasing in the treatment of many types of fractures, the
use of various metal structures, and the potential for infection with the
development of osteomyelitis accordingly increases. The urgency of the problem
is due to the fact that this disease is the most expensive medical problem,
especially when it comes to prosthetics of large joints, with socially
significant losses and the occurrence of disability in patients of working age,
it requires long-term treatment. The aim of this study was to study one of the
most complex pathogens of life-threatening infections due to its high virulence
and ability to adapt to changing environmental conditions, in particular the
action of antibacterial drugs and the study of its sensitivity to certain groups
of antimicrobial drugs. The results of the study showed that over the three
years of observation in 2017–2019, the average value of Pseudomonas
aeruginosa in the amount of 10.8% was established in the etiology of
osteomyelitis. The revealed sensitivity of Pseudomonas aeruginosa is preserved
to fluoroquinolone – levofloxanin, aminoglycosides-amikacin, gentamicin,
carbapenems – meropenem, doripenem. All of the above drugs can be used
as empirical therapy. During this period, a significant decrease in sensitivit...
Source: Drug Research - Category: Drugs & Pharmacology Authors: Pliska, Natalya N. Tags: Original Article Source Type: research
More News: Disability | Drugs & Pharmacology | Environmental Health | Microbiology | Osteomyelitis | Pathology | Study