Phloretin flavonoid exhibits selective antiproliferative activity in doxorubicin-resistant gastric cancer cells by inducing autophagy, inhibiting cell migration and invasion, cell cycle arrest and targeting ERK1/2 MAP pathway.

CONCLUSIONS: Phloretin may prove beneficial as a promising drug candidate for gastric cancer treatment provided further studies are carried out on it, especially toxicological studies. PMID: 32277647 [PubMed - as supplied by publisher]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research