Reduced CD4+ CD25++ CD45RA- Foxp3hi activated regulatory T cells and its association with acute rejection in patients with kidney transplantation.

CONCLUSION: Patients with AR had poorer immunoregulatory properties than those with normal graft functioning, as well as those in the control group. These reduced immunoregulatory properties in patients with AR could lead to graft rejection.
PMID: 32240775 [PubMed - as supplied by publisher]

Source: Transplant Immunology - March 29, 2020 Category: Transplant Surgery Authors: Mirzakhani M, Shahbazi M, Akbari R, Oliaei F, Asgharpour M, Nikoueinejad H, Mohammadnia-Afrouzi M Tags: Transpl Immunol Source Type: research