Detection and Implications of Occult Contralateral Nodal Spread in Human Papillomavirus –Associated Base of Tongue Cancer

To the Editor We congratulate Last et al for their valuable contribution to our understanding of the risk of contralateral nodal spread in patients with human papillomavirus (HPV) –associated squamous cell carcinoma of the base of the tongue. They report occult contralateral nodal involvement in 21.4% of the cohort and appropriately argue that this warrants bilateral neck management in patients with this disease. We have 2 questions that would be relevant to the head and ne ck oncology community.
Source: JAMA Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Source Type: research