Minimal clinically important difference in quality of life scores for patients with heart failure and reduced ejection fraction

ConclusionThe MCID threshold for KCCQ score was generally consistent and numerically lower than the threshold of 5 ‐point change considered for clinical outcome prognosis and were stable between 4 and 24 weeks. This suggests that even changes smaller than the traditional 5‐point improvements in KCCQ may be clinically meaningful. Also, these results can aid in the clinical interpretation of patient‐report ed outcomes, and better endpoint selection in future studies.

Source: European Journal of Heart Failure - April 1, 2020 Category: Cardiology Authors: Javed Butler, Muhammad Shahzeb Khan, Claudio Mori, Gerasimos S. Filippatos, Piotr Ponikowski, Josep Comin ‐Colet, Bernard Roubert, John A. Spertus, Stefan D. Anker Tags: Research Article Source Type: research