A novel mouse model of autoimmune thyroiditis induced by immunization with adenovirus containing full-length thyroglobulin cDNA: Implications to genetic studies of thyroid autoimmunity.

CONCLUSIONS: Our data describe a novel murine model of autoimmune thyroiditis which does not require the use of adjuvants to break down tolerance and that will allow investigators to test the effects of hTG variants in the pathoetiology of Hashimoto's thyroiditis (HT). PMID: 32228171 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research