Pathogenic Activation of Mesenchymal Stem Cells is induced by the Disease Microenvironment in Systemic Sclerosis

ConclusionDividing MSC ‐like cells are present in the SSc disease microenvironment where multiple factors, likely acting in concert, promote transdifferentiation, leading to a complex and resistant disease state.

Source: Arthritis and Rheumatology - March 30, 2020 Category: Rheumatology Authors: Zeinab Taki, Elena Gostjeva, William Thilly, Bodoor Yaseen, Henry Lopez, Maria Mirza, Zainab Hassuji, Shivanee Vigneswaran, Bahja Ahmed Abdi, Amy Hart, Nikita Arumalla, Gemma Thomas, Christopher P Denton, Yasir Suleman, Huan Liu, Cristina V Tags: FULL LENGTH Source Type: research