Pulmonary Markers of Epithelial Cell Activation and Injury in Chronic Lung Allograft Dysfunction

Airway epithelial injury is thought to be a key event in the pathogenesis of CLAD. We investigated whether markers of epithelial activation and injury in bronchoalveolar lavage (BAL) correlate with CLAD diagnosis and the major CLAD phenotypes: bronchiolitis obliterans syndrome (BOS) vs. restrictive allograft syndrome (RAS) / mixed phenotype.

Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: L. Levy, S. Moshkelgosha, E. Huszti, S. Hunter, B. Renaud-Picard, G. Berra, M. Kawashima, A. Takahagi, J. Fernandez-Castillo, E. Fuchs, R. Ghany, S. Keshavjee, L. Singer, J. Tikkanen, T. Martinu Tags: (386) Source Type: research