Associations Between Mutations in MSH6 and PMS2 and Risk of Surveillance-detected Colorectal Cancer
Lynch syndrome is the most common inherited cause of colorectal cancer (CRC). Contemporary and mutation-specific estimates of CRC-risk in patients undergoing colonoscopy would optimize surveillance strategies. We performed a prospective national cohort study, using data from New Zealand, to assess overall and mutation-specific risk of CRC in patients with Lynch syndrome undergoing surveillance.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Mehul Lamba, Chris Wakeman, Rosy Ebel, Sarah Hamilton, Chris Frampton, Maxene Kiesanowski, Ben Griffiths, John Keating, Susan Parry, Teresa Chalmers-Watson Source Type: research
More News: Cancer | Cancer & Oncology | Colonoscopy | Colorectal Cancer | Gastroenterology | HNPCC | Lynch Syndrome | New Zealand Health | Study