Nicorandil Inhibits Inflammasome Activation and Toll-Like Receptor-4 Signal Transduction to Protect against Oxygen-Glucose Deprivation-Induced Inflammation in BV-2 Cells.

CONCLUSIONS: Our findings reveal that KATP channel openers could protect against OGD-induced neuroinflammation via inhibiting inflammasome activation and TLR4 signal transduction. PMID: 24256503 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24256503?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - November 20, 2013 Category: Neuroscience Authors: Zhao AP, Dong YF, Liu W, Gu J, Sun XL Tags: CNS Neurosci Ther Source Type: research

More News: Brain | Brain Cancers | Neurology | Neuroscience | Study