Protective effects of histone deacetylase inhibition by Scriptaid on brain injury in neonatal rat models of cerebral ischemia and hypoxia.

CONCLUSION: After HBID, HDAC inhibitor Scriptaid inhibits inflammatory responses and protects the brain by promoting the polarization of microglia in brain tissue to M2 microglia. PMID: 32211098 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/32211098?dopt=Abstract

Source: International Journal of Clinical and Experimental Pathology - March 28, 2020 Category: Pathology Authors: Meng Q, Yang G, Yang Y, Ding F, Hu F Tags: Int J Clin Exp Pathol Source Type: research