GSE133039 Epigenetic footprint of hepatoblastoma defines a novel integrative molecular classification with clinical implications [RNA-seq]

Contributors : Juan Carrillo-Reixach ; Marina Simon-Coma ; Nicholas Akers ; Laura Royo ; Laura Torrens ; Magdalena Arnal ; Nuria Villalmanzo ; Stefano Cairo ; Alberto Villanueva ; Roland Kappler ; Montserrat Domingo-Sabat ; Marta Garrido ; Laura Guerra ; Constantino S ábado ; Gabriela Guillén ; Mar Mallo ; David Piñeyro ; María Vázquez-Vitali ; Olga Kuchuk ; María Mateos ; Gema Ramírez ; Manuel López Santamaría ; Yasmina Mozo ; Aroa Soriano ; Michael Grotzer ; Sophie Branchereau ; Nagore García de Andoin ; Blanca López-Ibor ; Ricardo Ló pez-Almaraz ; José Salinas ; Bárbara Torres ; Francisco Hernández ; José Uriz ; Monique Fabre ; Julià Blanco ; Claudia Paris ; Viera Bajčiová ; Geneviève Laureys ; Elena Masnou ; Cristina Belendez ; Catherine Guettier ; Lauro Sumoy ; Ramón Planas ; Mireia Jordà ; Lara Nonel l ; Piotr Czauderna ; Bruce Morland ; Margarita Sala ; Daniela Sia ; Bojan Losic ; Maria Sarrias ; Marie Buendia ; Josep Llovet ; Carolina ArmengolSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHepatoblastoma (HB) is the predominant pediatric liver cancer with limited therapeutic options for patients with aggressive tumors. Nevertheless, it is a rare disease. Here, we performed a high-throughput molecular study of 32 patients with HB and major findings were validated in additional 80 cases. We unveiled an epigenetic footprint including downregulation of RNA-ed...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research