Molecules, Vol. 25, Pages 1423: Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876 —A Less Toxic and More Potent Analogue of Bedaquiline

We report here our synthetic efforts to unequivocally structurally characterize these three metabolites through their independent directed synthesis.

Source: Molecules - March 19, 2020 Category: Chemistry Authors: Peter J. Choi Hamish S. Sutherland Adrian Blaser Amy S.T. Tong Christopher B. Cooper Anna M. Upton Brian D. Palmer William A. Denny Tags: Article Source Type: research