Joint Effect of ABCA7 rs4147929 and Body Mass Index on Progression from Mild Cognitive Impairment to Alzheimer's Disease: the Shanghai Aging Study.

CONCLUSION: ABCA7 rs4147929 and BMI jointly affect MCI-AD progression. MCI participants with the rs4147929 risk genotype may benefit from maintaining an overweight BMI level with regard to their risk for incident AD.
PMID: 32183673 [PubMed - as supplied by publisher]

Source: Current Alzheimer Research - March 15, 2020 Category: Neurology Authors: Xi J, Ding D, Zhao Q, Liang X, Zheng L, Guo Q, Hong Z, Fu H, Xu J, Xiao Q Tags: Curr Alzheimer Res Source Type: research