A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese

Conclusion: This NOTCH4 missense mutation decreased the risk for developing MS in Japanese, but did not affect clinical features of those who had already developed the disease.

http://msj.sagepub.com/cgi/content/abstract/19/13/1696?rss=1

Source: Multiple Sclerosis - November 11, 2013 Category: Neurology Authors: Huang, J., Yoshimura, S., Isobe, N., Matsushita, T., Yonekawa, T., Sato, S., Yamasaki, R., Kira, J.-i., the South Japan Multiple Sclerosis Genetics Consortium, Miyamoto, Kusunoki, Nakatsuji, Mochizuki, Ochi, Matsumoto, Kanda, Ochi, Miki, Okada, Tsuji Tags: Research Papers Source Type: research