Selective cytotoxic activity and protective effects of sodium ascorbate against hepatocellular carcinoma through its effect on oxidative stress and apoptosis in vivo and in vitro.

Conclusion: In spite of the antioxidant and anti-inflammatory activity of sodium ascorbate, it produced selective cytotoxic activity via direct activation of the apoptotic pathway in cancer cells without affecting the apoptotic pathway in normal hepatic cells. PMID: 32172678 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32172678?dopt=Abstract

Source: Redox Report : communications in free radical research - March 17, 2020 Category: Biochemistry Authors: El-Far YM, Khodir AE, Noor AO, Almasri DM, Bagalagel AA, Diri RM, Kutbi HI, Al-Gayyar MMH Tags: Redox Rep Source Type: research