Spontaneous reports of hypersensitivity adverse drug reactions in Portugal: a retrospective analysis.

Conclusions: Most hypersensitivity ADRs were serious, unexpected and with strong causal relationship with suspected drugs. Allopurinol was the top-causative drug. In addition to antibiotics and anti-inflammatories, antineoplastic agents were frequently cited. The results of this study deserve further investigation to better characterize risk factors associated with hypersensitivity ADRs, particularly in those induced by allopurinol and antineoplastic agents. PMID: 32167395 [PubMed - as supplied by publisher]
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research