Chronic aerobic exercise associated to low-dose L-NAME improves contractility without changing calcium handling in rat cardiomyocytes.

In conclusion, the association of chronic aerobic exercise and low-dose L-NAME prevented cardiac pathological remodeling and induced cardiomyocyte contractile function improvement; however, it did not alter myocyte affinity and sensitivity to intracellular Ca2+ handling.
PMID: 32159612 [PubMed - in process]

Source: Braz J Med Biol Res - March 13, 2020 Category: Research Authors: Luchi TC, Coelho PM, Cordeiro JP, Assis ALEM, Nogueira BV, Marques VB, Dos Santos L, Lima-Leopoldo AP, Lunz W, Leopoldo AS Tags: Braz J Med Biol Res Source Type: research