BACE2 degradation is mediated by both the proteasome and lysosome pathways

Alzheimer ’s disease is the most common neurodegenerative disease in the elderly. Amyloid-β protein (Aβ) is the major component of neuritic plaques which are the hallmark of AD pathology. β-site APP cleaving en...

Source: BMC Cell Biology - March 11, 2020 Category: Cytology Authors: Kaixin Qiu, Wenping Liang, Shuai Wang, Tingting Kong, Xin Wang, Chunyan Li, Zhe Wang and Yili Wu Tags: Research article Source Type: research