Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.

CONCLUSIONS: The neuroprotective and anti-inflammatory effects of DBD are associated with selective modulation of microglia polarization and reduction in the production of inflammatory mediators and cytokines through inhibition of MAPK and NF-κB activation. These findings suggest that DBD may be a potential treatment for ischemic stroke and other neuroinflammatory diseases. PMID: 32143007 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32143007?dopt=Abstract

Source: International Immunopharmacology - March 2, 2020 Category: Allergy & Immunology Authors: Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q Tags: Int Immunopharmacol Source Type: research