Ageing reduces angiotensin II type 1 receptor antagonism mediated pre-conditioning effects in ischemic kidneys by inducing oxidative and inflammatory stress.

CONCLUSION: We conclude that AT1 receptor antagonism is not beneficial against renal I/R induced AKI in aged rats. PMID: 32119995 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - Category: Geriatrics Authors: Tags: Exp Gerontol Source Type: research