Ageing reduces angiotensin II type 1 receptor antagonism mediated pre-conditioning effects in ischemic kidneys by inducing oxidative and inflammatory stress.
CONCLUSION: We conclude that AT1 receptor antagonism is not beneficial against renal I/R induced AKI in aged rats.
PMID: 32119995 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - Category: Geriatrics Authors: Ogbadu J, Singh G, Gupta K, Mehra K, Sen P Tags: Exp Gerontol Source Type: research
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