Co-occurrence of autistic and psychotic traits: implications for depression, self-harm and suicidality - Sampson KN, Upthegrove R, Abu-Akel A, Haque S, Wood SJ, Reniers R.

BACKGROUND: There is increasing interest in the clinical and aetiological overlap between autism spectrum disorders and schizophrenia spectrum disorders, reported to co-occur at both diagnostic and trait levels. Individually, sub-clinical autistic and psyc...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Related Links:

(Universit à di Trento) A research team coordinated by the University of Trento studied a mass of brain cells, the habenula, linked to disorders like autism, schizophrenia and depression. The results of their work, published in 'Development', will help find out more about serious brain disorders that can only be treated in ways that take a toll on the quality of life of people.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
AbstractPurpose of reviewThe purpose of the current study was to examine emotional overinvolvement (EOI) among caregivers of adolescents with a range of physical and psychiatric disorders to determine whether it is a problematic construct.Recent findingsExpressed emotion is a robust predictor of treatment dropout, outcome, and relapse across a range of physical and psychiatric disorders. The two components of expressed emotion that have received the most research attention are criticism and EOI. Although criticism plays a significant role in treatment outcome, evidence is mixed for EOI, particularly in children and adolesc...
Source: Current Treatment Options in Psychiatry - Category: Psychiatry Source Type: research
(University of Barcelona) An international study published in the journal Cell, has described 109 genetic variants associated with eight psychiatric disorders: autism, ADHD, schizophrenia, bipolar disorder, depression, obsessive-compulsive disorder and Tourette Syndrome, in a total of about 230,000 patients worldwide.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
AbstractSerotonin transporter (SERT) is involved in serotonergic system regulation and in the pathophysiology/therapeutics of serotonin ‐/SERT‐related diseases such as obsessive‐compulsive disorder, depression, autism and schizophrenia. We recently revealed that diacylglycerol (DG) kinase (DGK) δ induces ubiquitination/degradation of SERT in a DGK activity‐dependent manner through Praja‐1 E3 ubiquitin‐protein ligase. Ho wever, it is still unclear how Praja‐1 activity is regulated by DGKδ. Here, we reveal that 1‐stearoyl‐2‐docosahexaenoyl (18:0/22:6)‐phosphatidic acid (PA) and 18:0/22:6‐D...
Source: FEBS Letters - Category: Biochemistry Authors: Tags: RESEARCH LETTER Source Type: research
Catatonic syndromes are characterized by pure motor signs (e.g., catalepsy or waxy flexibility), disturbed volition (e.g., negativism), inability to suppress complex motor activities (e.g., echophenomena), and autonomic instability (1,2). They can occur not only in various psychiatric diseases, primarily schizophrenia, but also in depression, autism, intoxication, or autoimmune encephalitides, such as anti-NMDA receptor encephalitis (1,2). Indeed, catatonic symptoms occur in up to 70% of cases of anti-NMDA receptor encephalitis (3).
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Correspondence Source Type: research
The objectives of this study are: (i) to assess the frequency of self-stigma in a multicentric nonselected psychiatric rehabilitation SMI and ASD sample; and (ii) to investigate the correlates of elevated self-stigma in different SMI conditions and in ASD. METHODS.: A total of 738 SMI or ASD outpatients were recruited from the French National Centers of Reference for Psychiatric Rehabilitation cohort (REHABase). Evaluations included sociodemographic data, illness characteristics, and standardized scales for clinical severity, quality of life, satisfaction with life, wellbeing, personal recovery, a large cognitive batte...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
CONCLUSIONS.: This study provided an atlas of genetic correlations between psychiatric disorders and plasma proteome, providing novel clues for pathogenetic and biomarkers, therapeutic studies of psychiatric disorders. PMID: 32093803 [PubMed - in process]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Across the landscape of mental health research and diagnosis, there is a diverse range of questionnaires and interviews available for use by clinicians and researchers to determine patient treatment plans or investigate internal and external etiologies. Although individually, these tools have each been assessed for their validity and reliability, there is little research examining the consistency between them in terms of what symptoms they assess, and how they assess those symptoms. Here, we provide an analysis of 126 different questionnaires and interviews commonly used to diagnose and screen for 10 different disorder typ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Abstract BACKGROUND: There is increasing interest in the clinical and aetiological overlap between autism spectrum disorders and schizophrenia spectrum disorders, reported to co-occur at both diagnostic and trait levels. Individually, sub-clinical autistic and psychotic traits are associated with poor clinical outcomes, including increased depressive symptomatology, self-harming behaviour and suicidality. However, the implications when both traits co-occur remain poorly understood. The study aimed to (1) examine the relationship between autistic and psychotic traits and (2) determine if their co-occurrence increas...
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
This study investigated whether antenatal exposure to antidepressants (ADs) increases the risks of autism spectrum disorders (ASD), attention deficit/hyperactivity disorders (ADHD), schizophrenia and other mental illnesses, and cognitive and developmental deficits in infants or preschool children. PubMed, EMBASE, BIREME/BVS databases were searched to identify studies examining associations of ADs in pregnancy with neurodevelopmental and psychiatric disorders. Twenty studies addressed ASD and/or ADHD risks while 30 focused on developmental and cognitive deficits in infants or preschool children. Most studies detected no ass...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research
More News: Autism | Depression | International Medicine & Public Health | Physiology | Schizophrenia