Clinicopathological significance of microRNA ‐21 in extracellular vesicles of pleural lavage fluid of lung adenocarcinoma and its functions inducing the mesothelial to mesenchymal transition

ConclusionsEV ‐miR‐21 in pleural lavage fluid is important as a diagnostic and prognostic factor. Moreover, EV‐miR‐21 induces the MMT, which can form premetastatic niches of dissemination in the pleural cavity.

Source: Cancer Medicine - February 25, 2020 Category: Cancer & Oncology Authors: Shiori Watabe, Yoshinao Kikuchi, Shigeki Morita, Daisuke Komura, Satoe Numakura, Arisa Kumagai ‐Togashi, Masato Watanabe, Noriyuki Matsutani, Masafumi Kawamura, Masanori Yasuda, Hiroshi Uozaki Tags: ORIGINAL RESEARCH Source Type: research