Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction.

CONCLUSIONS: The current evidence from randomised controlled trials does not support or refute the clinical use of intracytoplasmic sperm injection (intracytoplasmic morphologically selected sperm injection (IMSI). We are very uncertain of the chances of having a live birth and of the risk of having a miscarriage. We found very low-quality evidence that IMSI may increase chances of a clinical pregnancy, which means that we are still very uncertain about any real difference. We did not find any trials reporting on the risk of congenital abnormalities. Well-designed and sufficiently powered trials are still required. PMID: 32083321 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32083321?dopt=Abstract

Source: Cochrane Database of Systematic Reviews - February 20, 2020 Category: General Medicine Authors: Teixeira DM, Hadyme Miyague A, Barbosa MA, Navarro PA, Raine-Fenning N, Nastri CO, Martins WP Tags: Cochrane Database Syst Rev Source Type: research