Effects of carvedilol on expression of TLR4 and its downstream signaling pathway in liver tissue of rats with cholestatic liver fibrosis.

CONCLUSIONS: Carvedilol can reduce the release of inflammatory mediators by down-regulating TLR4 expression and inhibiting its downstream signaling pathway, thus playing a potential therapeutic role in cholestatic liver fibrosis. PMID: 32077825 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32077825?dopt=Abstract

Source: Current Molecular Medicine - February 19, 2020 Category: Molecular Biology Authors: Tian X, Zhao H, Guo Z Tags: Curr Mol Med Source Type: research