Cancers, Vol. 12, Pages 500: Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13R α2-Promoted Invasion and Metastasis in Cancer Cells

Conclusions: We have uncovered that IL13 signaling through IL13Rα2 requires PTP1B activity and therefore, PTP1B inhibition represents a promising therapeutic strategy in multiple types of cancer, including glioblastoma.

Source: Cancers - February 20, 2020 Category: Cancer & Oncology Authors: Bartolom é Mart ín-Regalado Ja én Zannikou Zhang de los R íos Balyasnikova Casal Tags: Article Source Type: research