Clinical and histological features of immune-mediated necrotising myopathy: a multi-centre South Australian cohort study

The idiopathic inflammatory myopathies (IIMs) are a group of systemic autoimmune diseases characterised primarily by muscle inflammation but also potentially accompanied by a range of extra-muscular manifestations. Dermatomyositis (DM), polymyositis (PM) and inclusion body myositis (IBM) constitute well-characterised subtypes of IIM, with the entity of non-specific idiopathic inflammatory myopathy (NSIIM) being more recently described [1]. Whilst these IIM subtypes are distinguished on clinical, serological and histological grounds, they are unified by the presence of a typically prominent intramuscular lymphocytic infiltrate.

Source: Neuromuscular Disorders - February 17, 2020 Category: Neurology Authors: Jessica Day, Sophia Otto, Kathy Cash, Vidya Limaye Source Type: research