Metabolic correlates of cognitive impairment in mesial temporal lobe epilepsy

ConclusionsCognitive impairment in MTLE correlates with extratemporal hypometabolism, involving the mesial frontoparietal networks implicated in the DMN and suggesting a disconnection with the affected hippocampus. Asymmetric alterations of connectivity may sustain the predominant ACC and pC metabolic decrease in patients with cognitive impairment.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research