Manual acupuncture for patients with major depressive disorder and comorbid insomnia: Evidence from Polysomnography and serum biomarkers

Conclusion(1) MA may be a potential alternative therapy for improving MDD and comorbid insomnia (particularly in extending total sleep time and shortening wake-up duration and sleep latency) via upregulating the expression of NPY and downregulating the expression of SP; more importantly, this efficacy of acupuncture can not be replaced by sham-acupuncture acting on the same acupoints with the same treatment frequency. (2) There is insufficient evidence to prove that MA can effectively reduce the number of arousals.
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research