A Systematic Review on the Effects of Nonpharmacological Sleep Interventions on Cardiometabolic Risk or Disease Outcomes
Conclusion The mediating effects of sleep improvement on cardiometabolic risk/disease control were inconclusive. More research to examine the effect of sleep-related risk-factor modification on cardiovascular health is warranted.
This study included patients who underwent primary laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG). The primary outcome of interest was incisional SSI occurring within 30 days. Surgeries performed in 2015 were used in a derivation cohort and the predictive tool was validated against the 2016 cohort. A forward selection algorithm was used to build a logistic regression model predicting probability of SSI.ResultsA total of 274,187 patients were included with 71.7% being LSG and 28.3% LRYGB. 0.7% of patients had a SSI in which 71.0% had an incisional SSI, and 29.9% had an organ/spa...
Much more than just a cosmetic issue, obesity is associated with type 2 diabetes, heart disease, high blood pressure, stroke, fatty liver disease, sleep apnea, arthritis, gallbladder disease and more, according to the U.S. National Institute for Diabetes and Digestive and Kidney Diseases.
CONCLUSION: MS is beneficial where the main aim is to attain a significant and long-lasting weight loss results. The RCTs have depicted the superiority which surgical mechanisms hold over medically based therapy, for enhancing glycaemic control, and achieving remission of diabetes. This type of surgery improves life quality, reduces incidences of other obesity and diabetes relating diseases like microvascular illness, sleep apnea, fatal disorder, and fatty liver disease. PMID: 32077829 [PubMed - as supplied by publisher]
AbstractIntroductionSingle-anastomosis duodenal switch has been suggested to be an effective bariatric procedure that offers excellent weight loss and by lengthening the common channel the potential to reduce micronutrient deficiencies.PurposeTo evaluate the weight loss, comorbidity resolution and the 1-year nutritional outcomes of the single-anastomosis duodenal switch (SADS) procedure.SettingMultiple US Hospitals.MethodsFrom October 2014 to January 2017, 120 patients were enrolled at six sites across the USA and underwent the SADS procedure. Weight loss, comorbidities, quality of life, and adverse events were followed po...
CONCLUSION: The mediating effects of sleep improvement on cardiometabolic risk/disease control were inconclusive. More research to examine the effect of sleep-related risk-factor modification on cardiovascular health is warranted. PMID: 31985700 [PubMed - as supplied by publisher]
Abstract BACKGROUND: Despite the abundance of data documenting the consequences of poor sleep quality on blood pressure (BP), no previous study to our knowledge has addressed the impact of sleep improvement on resistant hypertension among patients with chronic kidney disease (CKD). METHODS: The aim of this pilot study was to determine whether improved sleep quality and duration will improve BP control in patients with resistant hypertension and CKD. It was a prospective single-center cohort study that involved 30 hypertensive subjects with CKD presenting with primary resistant hypertension and poor sleep quality or duration
ConclusionsSADI-S appears to be a safe bariatric surgical procedure with favorable outcomes at 2 years in the Australian population.
CONCLUSIONS: Our study has expanded the methodological utility of PRS in patient stratification and risk prediction, especially in a multifactorial condition like PCOS, across different genetic origins. By utilizing the individual genome-phenome data available from the EHR, our approach also demonstrates that polygenic prediction by PRS can provide valuable opportunities to discover the pleiotropic phenomic network associated with PCOS pathogenesis. PMID: 31917831 [PubMed - as supplied by publisher]
ConclusionBoth operations produced excellent weight loss and maintenance in the short to intermediate term. There was better resolution of T2D and HTN after OAGB/MGB at the expense of a higher incidence of nutrient deficiency and some protein caloric malnutrition. There is need for prospective and larger series studies to confirm these findings.
Publication date: Available online 30 November 2019Source: Obesity Research &Clinical PracticeAuthor(s): Maya Tsao-Wu, Ronald J. Williams, Helen M. Hendy, Marsha B. NovickAbstractBackgroundChildhood obesity has increased dramatically in the United States. Most available research has followed obesity prevalence with little attention to medical comorbidities, which could guide prevention and intervention.MethodsA retrospective chart review examined 2038 children referred to a Pediatric Weight Management Clinic providing low intensity (26 contact hours for changes in diet, exercise, screen time) for reducing obesity sever...