Frequency and Significance of Coronary Artery Disease and Myocardial Bridging in Patients with Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HC) is the most common inherited cardiac disease that affects at least 0,2% of the general population.1 Although many patients diagnosed with HC present without or with minimal physical symptoms, a substantial group will experience mild to severe chest pain. The etiology of chest pain in HC patients is complex and includes myocardial ischemia, an increased metabolic demand and reduced myocardial blood supply.1-3 HC patients are not exempt from coronary artery disease (CAD).
Source: The American Journal of Cardiology - Category: Cardiology Authors: Tags: Myocardial bridging in hypertrophic cardiomyopathy Source Type: research

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This study assesses clinical presentations and outcomes of patients with previous coronary revascularization undergoing septal myectomy.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
CONCLUSION: In this adult cohort of low-risk HCM athletes, voluntary decision to pursue in participation in competitive sport events was not associated with increased risk for major cardiac events or clinical worsening compared with decision to reduce or withdraw from exercise programmes and sport. Similar results may not be seen in younger or racially diverse athlete populations, or in patients with more severe HCM phenotypes. PMID: 32532845 [PubMed - as supplied by publisher]
Source: British Journal of Sports Medicine - Category: Sports Medicine Authors: Tags: Br J Sports Med Source Type: research
Authors: Han Z, Xu X, Lin Y Abstract A 67-year-old man was admitted to our hospital due to chest tightness induced by activity that had started about 2 months earlier. To clarify the causes of chest pain in this patient, cardiac magnetic resonance imaging was performed, resulting in a diagnosis of ventricular apical hypertrophic cardiomyopathy with intramyocardial calcification. PMID: 32240101 [PubMed - in process]
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Discussion Tachycardia is a rapid heart rate that is above normal for age and level of exertion. Tachycardia is common, particularly sinus tachycardia due to normally encountered circumstances such as pain, fever or exercise. It is usually a normal physiologic process but sustained tachycardia often indicates a potentially abnormal underlying cause. Sinus tachycardia has a rapid heart rate with normal P waves and P-R intervals and variations from moment to moment and respiration. Generally it is not over 200 beats/minute. Vagal stimulation can slow the heart rate; this is a gradual slowing, not an abrupt slowing seen in ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
This article, presented as a bibliographic review, reviews the clinical and cardiovascular imaging aspects in this scenario of cardiomyopathy in a rare metabolic disease, based on the latest scientific evidence published in the area. Despite the frequent association of congenital lipodystrophy and ventricular hypertrophy described in the literature, the pathophysiological mechanisms of this cardiomyopathy have not yet been definitively elucidated, and new information on cardiac morphological aspects is emerging in the aegis of recent and advanced imaging methods, such as cardiac magnetic resonance.Resumo A lipodistrofia fa...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
ConclusionSeptal myectomy is safe and effective. Concomitant mitral operations do not increase morbidity and mortality.
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Conclusions: In summary, we report on a case of transient global ventricular wall thickening secondary to acute myocarditis, which rarely has been described previously. Our study demonstrates that transient ventricular wall thickening related to myocardial interstitial edema also can involve the right ventricular wall, a fact that is important in diagnosis and differential diagnosis. Cardiovascular magnetic resonance currently is considered the most comprehensive and accurate diagnostic tool in patients with suspected myocarditis.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
A 50-something with sudden severe epigastric and chest pain presented looking extremely ill.Here is her ECG:What do you think?There is ST Elevation in V2-V6, worrisome for ischemia.Or is it?Notice the very large R-waves and the very prominent J-point notching, with small S-waves.This is typical ofBenign T-wave Inversion, which is commonly seen in black patients of African heritage.This case was sent from Australia and the patient was aboriginal.  I have never heard of or seen benign T-wave inversion in Australian aboriginal blacks.The cath lab was activated and the patient was taken for angiogram, which was norma...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
In conclusion, both painless ischemia and painful ischemia are associated with a gradual, significant increase in NT-proBNP/ULN in comparison to the double-negative hsTnI/AP subgroup. In contrast, NT-proBNP is significantly higher in only the subgroup with painful ischemia. PMID: 31320942 [PubMed - in process]
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Authors: Parlar-Chun R, Kakarala K, Singh M Abstract Patients hospitalized for asthma can exhibit concurrent cardiac symptoms and undergo cardiac work up. We identify patients admitted for asthma that underwent cardiac workup and describe outcomes to evaluate the utility of cardiac testing in this population. Patients aged 4 to 17 years admitted for status asthmaticus from 2012 - 2016 were screened for EKG, ECHO, or cardiac enzyme obtainment. Out of 1296 patients, 77 (6%) received cardiac testing. The most common reasons for testing were chest pain (25, 32%), blood pressure abnormalities (11, 14%), tachycardia (8, ...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
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