Ginsenoside Rb1 inhibits monoiodoacetate-induced osteoarthritis in postmenopausal rats through prevention of cartilage degradation

ConclusionOverall, our results suggest that G-Rb1 exerts cartilage protective effect on MIA-induced ovariectomized OA rats, by inhibiting inflammatory mediators such as IL-6, IL-1β, monocyte chemoattractant protein-1/CCL2, COX-2, and PGE2. These results shed a light on possible therapeutic application of G-Rb1 in OA.
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research