High heart rate at admission as a predictive factor of mortality in hospitalized patients with Lassa fever: An observational cohort study in Sierra Leone

Wauquier et al., in the Journal, shown that heart rate level greater than 110 bpm at hospital admission for Lassa Fever (LF) is an independent predictive factor associated with a 3.6-fold increased risk of mortality. An estimated 100,000 to 300,000 infections of Lassa fever occur annually, with approximately 5,000 deaths., mainly in West Africa.1,2 Despite this high annual mortality rate, LF has been largely underappreciated regarding its contribution to the overall burden of microbial infections, and particularly in Sierra Leone.

Source: Journal of Infection - February 2, 2020 Category: Infectious Diseases Authors: Nadia Wauquier, Camille Couffignal, Pauline Manchon, Elisabeth Smith, Victor Lungay, Moinya Coomber, Lauren Weisenfluh, James Bangura, Sheik Humarr Khan, Amara Jambai, Aiah Gbakima, Nadezda Yun, Slobodan Paessler, Randal Schoepp, Stephen S. Morse, Jean-Pa Source Type: research