Therapeutic approaches targeting Apolipoprotein E function in Alzheimer ’s disease

One of the primary genetic risk factors for Alzheimer ’s disease (AD) is the presence of the Ɛ4 allele of apolipoprotein E (APOE). APOE is a polymorphic lipoprotein that is a major cholesterol carrier in the br...

Source: Molecular Neurodegeneration - January 31, 2020 Category: Neurology Authors: Tosha Williams, David R. Borchelt and Paramita Chakrabarty Tags: Review Source Type: research