Synbiotic Alters Fecal Microbiomes, but not Liver Fat or Fibrosis, in a Randomized Trial of Patients With Non-alcoholic Fatty Liver Disease

Dysbiosis of the intestinal microbiota has been associated with nonalcoholic fatty liver disease (NAFLD). We investigated whether administration of a synbiotic combination of probiotic and prebiotic agents affected liver fat content, biomarkers of liver fibrosis, and the composition of the fecal microbiome in patients with NAFLD.

Source: Gastroenterology - January 23, 2020 Category: Gastroenterology Authors: Eleonora Scorletti, Paul R. Afolabi, Elizabeth A. Miles, Debbie E. Smith, Amal Almehmadi, Albandri Alshathry, Caroline E. Childs, Stefania Del Fabbro, Josh Beavis, Helen E. Moyses, Geraldine F. Clough, Jaswinder K. Sethi, Janisha Patel, Mark Wright, David Source Type: research