Reduced Autoimmune Cytopenias after Cord Blood Transplant in Pediatric Patients with Nonmalignant Disease Conditioned without Serotherapy

Autoimmune cytopenias (AIC) are a known complication of hematopoietic stem cell transplant that can lead to increased morbidity and mortality. Higher rates of AIC have been reported in patients transplanted for nonmalignant conditions ranging from 19.5%-56% with the highest rate reported in very young infants ( ≤3 months) with non-malignant diseases who had undergone unrelated cord blood transplants following ablative conditioning with serotherapy.

Source: Biology of Blood and Marrow Transplantation - January 24, 2020 Category: Hematology Authors: Julie Klinger, Paibel Aguayo-Hiraldo, Nicholas I. Rider, Sarah K. Nicholas, Lisa Forbes, Filiz O. Seeborg, Lenora M. Noroski, Bilal Omer, Tami John, Khaled Yassine, Swati Naik, John Craddock, David H.M. Steffin, Erin E. Doherty, Carl Allen, Nabil M. Ahmed Tags: 317 Source Type: research