The Association of Leukocyte Immunoglobulin-like Receptor B4 (LILRB-4) with Central Nervous System Involvement in Patients with Acute Myeloid Leukemia

The prevalence of central nervous system (CNS) involvement in patients with acute myeloid leukemia (AML) is variable with a reported range of 0.6% to 46%. Unfortunately, the clinical consequences of untreated CNS involvement in AML which include complete paraplegia and bilateral total blindness, can be devastating. In addition, both the diagnostic evaluation and treatment of CNS involvement are associated with potential significant morbidity. Thus, there is a need to predict CNS involvement in a noninvasive manner in patients with AML.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 151 Source Type: research