Phase separation provides a mechanism to reduce noise in cells

In this study, we used a physical model that links noise in protein concentration to theory of phase separation to show that liquid droplets can effectively reduce noise. We provide experimental support for noise reduction by phase separation using engineered proteins that form liquid-like compartments in mammalian cells. Thus, phase separation can play an important role in biological signal processing and control.

Source: ScienceNOW - January 22, 2020 Category: Science Authors: Klosin, A., Oltsch, F., Harmon, T., Honigmann, A., Jülicher, F., Hyman, A. A., Zechner, C. Tags: Biochemistry, Cell Biology reports Source Type: news