Association Between Glutathione- S -Transferase Gene Polymorphisms and Responses to Tyrosine Kinase Inhibitor Treatment in Patients with Chronic Myeloid Leukemia: A Meta-analysis

ConclusionsThis meta-analysis of patients with CML showed that G allele carriers withGSTP1 Ile105Val polymorphism had significantly worse responses to TKI treatment than wild-type homozygote carriers.

Source: Targeted Oncology - January 22, 2020 Category: Cancer & Oncology Source Type: research