Urinary Tract Infections Caused by Community-Acquired Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in a Level III Hospital - A Retrospective Study.
CONCLUSION: Although the number of cases is small, the clinical and microbiological outcomes showed that most were successfully treated with non-carbapenem antibiotics, with low recurrence of new episodes of urinary tract infections. PMID: 31962058 [PubMed - as supplied by publisher]
Authors: Mann M, Calio BP, Mark JR, Chelluri R, Hufnagel E, Reese A, Lallas CD, Trabulsi EJ, Chandrasekar T, Shenot PJ, Halpern E, Gomella LG Abstract INTRODUCTION: To assess whether standard American Urological Association (AUA) and other recommendations for prostate biopsy prophylaxis provide sufficient coverage of common urinary organisms responsible for post biopsy infections by comparing local antibiograms in Philadelphia-area hospitals. MATERIALS AND METHODS: De-identified culture results derived from antibiograms were collected from six academic and community hospitals in the Philadelphia region. Analysi...
Publication date: Available online 12 February 2020Source: Microbial PathogenesisAuthor(s): Imran Khan, Ashutosh Bahuguna, Shruti Shukla, Faisal Aziz, Anil Kumar Chauhan, Mohd Bismillah Ansari, Vivek K. Bajpai, Yun Suk Huh, Sun Chul KangAbstractThe antibiotic resistance of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli has increased drastically in recent years. In our study, we determined the principle mechanisms of action for the food-grade additive carvacrol against ESBL E. coli isolated from the blood of patients with a urinary tract infection. Carvacrol, which has a minimum inhibitory concentratio...
ConclusionsIn ESBL-E. coli RUTI, most recurrences were caused by the initial infecting strain. The high frequency of the multidrug-resistant fimH30Rx subclone and its association with multiple recurrences warrants further attention and early detection of this subclone in patients at risk of developing RUTI with ESBL-producing E. coli.
ConclusionsOur study shows that fosfomycin-resistantE. coli strains are isolated in the majority of the cases in elderly people with complicated UTIs and belong the pandemic ST131 clone. To our knowledge, we describe, for the first time in Spain, the gene fosA3, which alerts for a future dissemination that should be monitored.
Antimicrobial resistance in N'Djamena (Chad): Four-year experience of the French Forward Medical and Surgical Team engaged in the "Barkhane Operation". Med Mal Infect. 2020 Feb 05;: Authors: Cardinale M, Bourbotte-Salmon F, Scheiwe C, Boulezaz S, Ridet M, Laitselart P Abstract OBJECTIVES: Knowledge of local antimicrobial resistance (AMR) patterns is required for effective empirical treatment of bacterial diseases. Very little is known about current resistance patterns of common pathogenic bacteria in the African region and particularly in the Sahel region. We aimed to describe the local bacte...
ConclusionCirculating MAIT cells in immunocompetent individuals with RUTIs respond to bacterial stimuli with reduced efficacy, which suggests that they are involved in the pathogenesis of RUTIs.
In conclusion, gas under the diaphragm can be related to non-bowel-related gynaecological pathology, but it vital to rule out sinister causes.
Conclusions:The results of this study showed that the most common resistance are antibiotics that are commonly used. The most effective antibiotics forE. coliwere imipenem, nitrofurantoin, amikacin, chloramphenicol, and ciprofloxacin. Considering this study, it had better, use less gentamicin, second ‑generation cephalosporins, and nalidixic acid in the initial treatment of infections caused byE. coli, and no use penicillins, tetracyclines, cotrimoxazole, and first-generation cephalosporins.Keywords:Antibiotics, antimicrobial resistance, Gram ‑negative bacteria, Gram‑positive bacteria, urinary tract infections
CONCLUSIONS Our research demonstrated that virulence factors were distributed among different phylogroup/subgroups, which play a role in UTIs pathogenesis in humans. For this reason, complex and detailed studies are required to determine the relationship between virulence factors and specific E. coli strains that cause UTIs in humans.