Drug therapy for delirium in terminally ill adults.
CONCLUSIONS: We found no high-quality evidence to support or refute the use of drug therapy for delirium symptoms in terminally ill adults. We found low-quality evidence that risperidone or haloperidol may slightly worsen delirium symptoms of mild to moderate severity for terminally ill people compared with placebo. We found moderate- to low-quality evidence that haloperidol and risperidone may slightly increase extrapyramidal adverse events for people with mild- to moderate-severity delirium. Given the small number of studies and participants on which current evidence is based, further research is essential.
PMID: 31960954 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Finucane AM, Jones L, Leurent B, Sampson EL, Stone P, Tookman A, Candy B Tags: Cochrane Database Syst Rev Source Type: research
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