Resibufogenin (RB) Inhibited Colorectal Cancer Cell Growth and Tumorigenesis through Triggering Ferroptosis and ROS Production Mediated by GPX4 Inactivation.

CONCLUSION: RB can inhibit CRC cells growth and tumorigensis by triggering ferroptotic cell death in a GPX4 inactivation dependent manner. This article is protected by copyright. All rights reserved. PMID: 31961485 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31961485?dopt=Abstract

Source: Anatomical Record - January 20, 2020 Category: Anatomy Authors: Shen LD, Qi WH, Bai JJ, Zuo CY, Bai DL, Gao WD, Zong XL, Hao TT, Ma Y, Cao GC Tags: Anat Rec (Hoboken) Source Type: research