Noninvasive sublingual microvascular imaging reveals sex ‐specific reduction in glycocalyx barrier properties in patients with coronary artery disease

ConclusionsOur data suggest that patients with CAD are characterized by a reduction in percentage of time microvessels are occupied by RBCs. In addition, CAD is significantly associated with impaired sublingual microvascular glycocalyx barrier function in women but not men. More research is needed to determine the significance of peripheral microvascular dysfunction in the pathophysiology of CAD, and how this may differ by sex.

Source: Physiological Reports - January 19, 2020 Category: Physiology Authors: Judith Brands, Carl A. Hubel, Andrew Althouse, Steven E. Reis, John J. Pacella Tags: ORIGINAL RESEARCH Source Type: research