Genetic and functional analysis of two missense mutations in CD46 predispose to postpartum atypical hemolytic uremic syndrome.

This study reported the first case of a four-generation postpartum-aHUS pedigree with isolated CD46 variants and the detailed disease progression, treatment, and prognosis provided more meaningful information for the understanding the disease.
PMID: 31945341 [PubMed - as supplied by publisher]

Source: International Journal of Clinical Chemistry - January 12, 2020 Category: Chemistry Authors: Wu H, Mao Z, Tan Y, Jiang Y, Yu J, Song L, Wu S, Sun M, Zhu L, Yu X, Zhang L, Yu F, Zhao MH Tags: Clin Chim Acta Source Type: research